human UBXN11 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human UBXN11.
shADV-227090
Ad-h-UBXN11-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human UBXN11 (UBX domain protein 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
COA-1; PP2243; SOC; SOCI; UBXD5
Description (Vector)
UBXN11 encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
91544
Gene Name (Vector)
UBX domain protein 11
Gene Symbol
UBXN11
HGNC ID
HGNC:30600
ORF Size (aa)
975
RefSeq ID
NM_183008
RefSeq Synonyms
NM_183008, NM_145345, NM_001077262, BC038106,
Species
human
UniGene ID
Hs.145061
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.