human TREM2 Over-expression AAV

Name 
AAV-h-TREM2
Cat No 
AAV-226366
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TREM2.

AAV-226366
AAV-h-TREM2

Ready-to-use AAV expressing Human TREM2 (triggering receptor expressed on myeloid cells 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TREM-2; Trem2a; Trem2b; Trem2c
Description (Vector)
TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
Gene ID
54209
Gene Name (Vector)
triggering receptor expressed on myeloid cells 2
Gene Symbol
TREM2
HGNC ID
HGNC:17761
ORF Size (aa)
669
RefSeq ID
NM_018965
RefSeq Synonyms
NM_018965, NM_001271821, BC032362,
Species
human
UniGene ID
Hs.435295

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.