human TREM2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TREM2.
shAAV-226366
AAV-h-TREM2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TREM2 (triggering receptor expressed on myeloid cells 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TREM-2; Trem2a; Trem2b; Trem2c
Description (Vector)
TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
Gene ID
54209
Gene Name (Vector)
triggering receptor expressed on myeloid cells 2
Gene Symbol
TREM2
HGNC ID
HGNC:17761
ORF Size (aa)
669
RefSeq ID
NM_018965
RefSeq Synonyms
NM_018965, NM_001271821, BC032362,
Species
human
UniGene ID
Hs.435295
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.