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mouse TREM2 shRNA silencing AAV

Name 
AAV-m-TREM2-shRNA
Cat No 
shAAV-274932
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Trem2.

shAAV-274932
AAV-m-TREM2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Trem2 (triggering receptor expressed on myeloid cells 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
84
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TREM-2; Trem2a; Trem2b; Trem2c
Description (Vector)
TREM2 may have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
Gene ID
83433
Gene Name (Vector)
triggering receptor expressed on myeloid cells 2
Gene Symbol
Trem2
ORF Size (aa)
684
RefSeq ID
NM_031254
RefSeq Synonyms
NM_031254, NM_001272078, BC052784, BC033485, BC032959,
Species
mouse
UniGene ID
Mm.261623

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.