human TNFRSF10B Over-expression AAV

Name 
AAV-h-TNFRSF10B
Cat No 
AAV-226069
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TNFRSF10B.

AAV-226069
AAV-h-TNFRSF10B

Ready-to-use AAV expressing Human TNFRSF10B (TNF receptor superfamily member 10b). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9
Description (Vector)
TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Gene ID
8795
Gene Name (Vector)
TNF receptor superfamily member 10b
Gene Symbol
TNFRSF10B
HGNC ID
HGNC:11905
ORF Size (aa)
1323
ORF Size (bp)
1323 bp
RefSeq ID
NM_003842
RefSeq Synonyms
NM_147187, NM_003842, BC001281,
Species
human
UniGene ID
Hs.521456

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.