human TNFRSF10B Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-226069
Availability:
3-5 weeks
Name:
AAV-h-TNFRSF10B
This is an AAV expressing Human TNFRSF10B.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- TNFRSF10B
- Gene Name
- TNF receptor superfamily member 10b
- Gene ID
- 8795
- Gene Synonyms
- CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9
- ORF Size
- 1323 bp
- RefSeq#
- BC001281
- Gene Description
- TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
- UniGene ID
- Hs.521456
- HGNC ID
- HGNC:11905
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