human TMF1 Over-expression AAV

Name 
AAV-h-TMF1
Cat No 
AAV-225990
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TMF1.

AAV-225990
AAV-h-TMF1

Ready-to-use AAV expressing Human TMF1 (TATA element modulatory factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
androgen receptor coactivator 160 kDa protein; androgen receptor-associated protein of 160 kDa; ARA160; TATA element modulatory factor; TMF
Description (eCommerce)
TATA element modulatory factor (TFM1), also known as androgen receptor-associated protein of 160 kDa (ARA160), is a potential co-activator of the androgen receptor. TFM1 mediates STAT3 degradation. It also may play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P82094].
Gene ID
7110
Gene Name (eCommerce)
TATA element modulatory factor 1
Gene Name (Vector)
TATA element modulatory factor 1
Gene Symbol
TMF1
HGNC ID
HGNC:11870
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3282
ORF Size (bp)
3282 bp
Protein Name (eCommerce)
TATA element modulatory factor
RefSeq ID
NM_007114
RefSeq Synonyms
NM_007114, BC143840, BC126123, BC117418,
Research Areas
Golgi Apparatus,Nuclear Receptor Coactivators,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
TATA element modulatory factor (TFM1), also known as androgen receptor-associated protein of 160 kDa (ARA160), is a potential co-activator of the androgen receptor. TFM1 mediates STAT3 degradation. It also may play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P82094].
UniGene ID
Hs.267632
UniProt ID (eCommerce)
P82094

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.