Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human TMF1 shRNA silencing AAV

Name 
AAV-h-TMF1-shRNA
Cat No 
shAAV-225988
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TMF1.

shAAV-225988
AAV-h-TMF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TMF1 (TATA element modulatory factor 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
androgen receptor coactivator 160 kDa protein; androgen receptor-associated protein of 160 kDa; ARA160; TATA element modulatory factor; TMF
Description (eCommerce)
TATA element modulatory factor (TFM1), also known as androgen receptor-associated protein of 160 kDa (ARA160), is a potential co-activator of the androgen receptor. TFM1 mediates STAT3 degradation. It also may play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P82094].
Gene ID
7110
Gene Name (eCommerce)
TATA element modulatory factor 1
Gene Name (Vector)
TATA element modulatory factor 1
Gene Symbol
TMF1
HGNC ID
HGNC:11870
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3282
ORF Size (bp)
3282 bp
Protein Name (eCommerce)
TATA element modulatory factor
RefSeq ID
NM_007114
RefSeq Synonyms
NM_007114, BC143840, BC126123, BC117418,
Research Areas
Golgi Apparatus,Nuclear Receptor Coactivators,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
TATA element modulatory factor (TFM1), also known as androgen receptor-associated protein of 160 kDa (ARA160), is a potential co-activator of the androgen receptor. TFM1 mediates STAT3 degradation. It also may play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P82094].
UniGene ID
Hs.267632
UniProt ID (eCommerce)
P82094

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.