human TMEM106B Over-expression AAV

Name 
AAV-h-TMEM106B
Cat No 
AAV-225698
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TMEM106B.

AAV-225698
AAV-h-TMEM106B

Ready-to-use AAV expressing Human TMEM106B (transmembrane protein 106B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HLD16; transmembrane protein 106B
Description (eCommerce)
Transmembrane protein 106B (TMEM106B) is a single-pass membrane protein expressed in the frontal cortex. Particular polymorphisms in the TMEM106B gene are associated with frontotemporal lobar degeneration with TAR DNA-binding protein inclusions (FTLD-TDP).
Gene ID
54664
Gene Name (eCommerce)
transmembrane protein 106B
Gene Name (Vector)
transmembrane protein 106B
Gene Symbol
TMEM106B
HGNC ID
HGNC:22407
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
825
ORF Size (bp)
825 bp
Protein Name (eCommerce)
Transmembrane protein 106B
RefSeq ID
NM_018374
RefSeq Synonyms
NM_018374, NM_001134232, BC039741, BC033901,
Research Areas
Amyotrophic Lateral Sclerosis (ALS),Lysosome,Neurobiology,Neurodegeneration
Research Areas (Faceted)
neurobiology,cell_biology
Species
human
Target Sentence
Transmembrane protein 106B (TMEM106B) is a single-pass membrane protein expressed in the frontal cortex. Particular polymorphisms in the TMEM106B gene are associated with frontotemporal lobar degeneration with TAR DNA-binding protein inclusions (FTLD-TDP).
UniGene ID
Hs.396358
UniProt ID (eCommerce)
Q9NUM4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.