human TMEM106B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TMEM106B.
shADV-225698
Ad-h-TMEM106B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TMEM106B (transmembrane protein 106B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HLD16; transmembrane protein 106B
Description (eCommerce)
Transmembrane protein 106B (TMEM106B) is a single-pass membrane protein expressed in the frontal cortex. Particular polymorphisms in the TMEM106B gene are associated with frontotemporal lobar degeneration with TAR DNA-binding protein inclusions (FTLD-TDP).
Gene ID
54664
Gene Name (eCommerce)
transmembrane protein 106B
Gene Name (Vector)
transmembrane protein 106B
Gene Symbol
TMEM106B
HGNC ID
HGNC:22407
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
825
ORF Size (bp)
825 bp
Protein Name (eCommerce)
Transmembrane protein 106B
RefSeq ID
NM_018374
RefSeq Synonyms
NM_018374, NM_001134232, BC039741, BC033901,
Research Areas
Amyotrophic Lateral Sclerosis (ALS),Lysosome,Neurobiology,Neurodegeneration
Research Areas (Faceted)
neurobiology,cell_biology
Species
human
Target Sentence
Transmembrane protein 106B (TMEM106B) is a single-pass membrane protein expressed in the frontal cortex. Particular polymorphisms in the TMEM106B gene are associated with frontotemporal lobar degeneration with TAR DNA-binding protein inclusions (FTLD-TDP).
UniGene ID
Hs.396358
UniProt ID (eCommerce)
Q9NUM4
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.