human STX5 Over-expression AAV

Name 
AAV-h-STX5
Cat No 
AAV-224667
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human STX5.

AAV-224667
AAV-h-STX5

Ready-to-use AAV expressing Human STX5 (syntaxin 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SED5; STX5A; syntaxin 5A; syntaxin-5
Description (eCommerce)
Syntaxin-5 (STX5) mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2,it is involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13190].
Description (Vector)
STX5 encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
6811
Gene Name (eCommerce)
syntaxin 5
Gene Name (Vector)
syntaxin 5
Gene Symbol
STX5
HGNC ID
HGNC:11440
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1068
Protein Name (eCommerce)
Syntaxin-5
RefSeq ID
NM_003164
RefSeq Synonyms
NM_003164, NM_001330294, NM_001244666, BC012137, BC002645,
Research Areas
Golgi Apparatus,Neurobiology
Research Areas (Faceted)
cell_biology,neurobiology
Species
human
Target Sentence
Syntaxin-5 (STX5) mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2,it is involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13190].
UniGene ID
Hs.654602
UniProt ID (eCommerce)
Q13190

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.