human STX5 shRNA silencing Adenovirus

Name 
Ad-h-STX5-shRNA
Cat No 
shADV-224667
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human STX5.

shADV-224667
Ad-h-STX5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human STX5 (syntaxin 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SED5; STX5A; syntaxin 5A; syntaxin-5
Description (eCommerce)
Syntaxin-5 (STX5) mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2,it is involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13190].
Description (Vector)
STX5 encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
6811
Gene Name (eCommerce)
syntaxin 5
Gene Name (Vector)
syntaxin 5
Gene Symbol
STX5
HGNC ID
HGNC:11440
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1068
Protein Name (eCommerce)
Syntaxin-5
RefSeq ID
NM_003164
RefSeq Synonyms
NM_003164, NM_001330294, NM_001244666, BC012137, BC002645,
Research Areas
Golgi Apparatus,Neurobiology
Research Areas (Faceted)
cell_biology,neurobiology
Species
human
Target Sentence
Syntaxin-5 (STX5) mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2,it is involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13190].
UniGene ID
Hs.654602
UniProt ID (eCommerce)
Q13190

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.