human STEAP4 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-224559
Availability:
3-5 weeks
Name:
AAV-h-STEAP4
This is an AAV expressing Human STEAP4.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- STEAP4
- Gene Name
- STEAP4 metalloreductase
- Gene ID
- 79689
- Gene Synonyms
- STAMP2; TIARP; TNFAIP9
- ORF Size
- 852 bp
- RefSeq#
- BC020600
- Gene Description
- STEAP4 belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.521008
- HGNC ID
- HGNC:21923
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