human STEAP4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human STEAP4.
shADV-224559
Ad-h-STEAP4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human STEAP4 (STEAP4 metalloreductase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
STAMP2; TIARP; TNFAIP9
Description (Vector)
STEAP4 belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
79689
Gene Name (Vector)
STEAP4 metalloreductase
Gene Symbol
STEAP4
HGNC ID
HGNC:21923
ORF Size (aa)
852
RefSeq ID
NM_024636
RefSeq Synonyms
NM_024636, NM_001205316, NM_001205315, BC020600,
Species
human
UniGene ID
Hs.521008
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.