human ST6GALNAC1 Over-expression AAV

Name 
AAV-h-ST6GALNAC1
Cat No 
AAV-224467
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ST6GALNAC1.

AAV-224467
AAV-h-ST6GALNAC1

Ready-to-use AAV expressing Human ST6GALNAC1 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HSY11339; SIAT7A; ST6GalNAcI; STYI
Description (Vector)
Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 (PubMed 10536037); Sewell et al., 2006 (PubMed 16319059)).(supplied by OMIM, Mar 2008)
Gene ID
55808
Gene Name (Vector)
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Gene Symbol
ST6GALNAC1
HGNC ID
HGNC:23614
ORF Size (aa)
1416
ORF Size (bp)
1416 bp
RefSeq ID
NM_018414
RefSeq Synonyms
NM_018414, NM_001289107, BC022462,
Species
human
UniGene ID
Hs.105352

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.