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human ST6GALNAC1 shRNA silencing Adenovirus

Name 
Ad-h-ST6GALNAC1-shRNA
Cat No 
shADV-224467
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ST6GALNAC1.

shADV-224467
Ad-h-ST6GALNAC1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ST6GALNAC1 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HSY11339; SIAT7A; ST6GalNAcI; STYI
Description (Vector)
Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 (PubMed 10536037); Sewell et al., 2006 (PubMed 16319059)).(supplied by OMIM, Mar 2008)
Gene ID
55808
Gene Name (Vector)
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Gene Symbol
ST6GALNAC1
HGNC ID
HGNC:23614
ORF Size (aa)
1416
ORF Size (bp)
1416 bp
RefSeq ID
NM_018414
RefSeq Synonyms
NM_018414, NM_001289107, BC022462,
Species
human
UniGene ID
Hs.105352

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.