human PPP2R4 Over-expression AAV

Name 
AAV-h-PPP2R4
Cat No 
AAV-219662
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PTPA.

AAV-219662
AAV-h-PPP2R4

Ready-to-use AAV expressing Human PTPA (protein phosphatase 2 phosphatase activator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PP2A; PPP2R4; PR53
Description (Vector)
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
5524
Gene Name (Vector)
protein phosphatase 2 phosphatase activator
Gene Symbol
PTPA
HGNC ID
HGNC:9308
ORF Size (aa)
972
RefSeq ID
NM_178001
RefSeq Synonyms
NM_178003, NM_178001, NM_178000, NM_021131, NM_001271832, NM_001193397, BC011605, BC002545,
Species
human
UniGene ID
Hs.400740

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.