human PRICKLE1 Over-expression AAV
This is an AAV expressing Human PRICKLE1.
AAV-219820
AAV-h-PRICKLE1
Ready-to-use AAV expressing Human PRICKLE1 (prickle planar cell polarity protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EPM1B; RILP
Description (Vector)
PRICKLE1 encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3.
Gene ID
144165
Gene Name (Vector)
prickle planar cell polarity protein 1
Gene Symbol
PRICKLE1
HGNC ID
HGNC:17019
ORF Size (aa)
2496
ORF Size (bp)
2496 bp
RefSeq ID
NM_153026
RefSeq Synonyms
NM_153026, NM_001144883, NM_001144882, NM_001144881, BC114940, BC114939,
Species
human
UniGene ID
Hs.639400
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.