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mouse PRICKLE1 shRNA silencing AAV

Name 
AAV-m-PRICKLE1-shRNA
Cat No 
shAAV-269349
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Prickle1.

shAAV-269349
AAV-m-PRICKLE1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Prickle1 (prickle planar cell polarity protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110058P22Rik; AW215793; b2b019Clo; mpk1; Prickle
Description (Vector)
Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.
Gene ID
106042
Gene Name (Vector)
prickle planar cell polarity protein 1
Gene Symbol
Prickle1
ORF Size (aa)
2499
ORF Size (bp)
2499 bp
RefSeq ID
NM_001033217
RefSeq Synonyms
NM_001033217, BC117893, BC117892,
Species
mouse
UniGene ID
Mm.476820

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.