human PPIB Over-expression AAV

Name 
AAV-h-PPIB
Cat No 
AAV-219549
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PPIB.

AAV-219549
AAV-h-PPIB

Ready-to-use AAV expressing Human PPIB (peptidylprolyl isomerase B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CYP-S1; CYPB; HEL-S-39; OI9; SCYLP
Description (Vector)
PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
Gene ID
5479
Gene Name (Vector)
peptidylprolyl isomerase B
Gene Symbol
PPIB
HGNC ID
HGNC:9255
ORF Size (aa)
651
RefSeq ID
NM_000942
RefSeq Synonyms
NM_000942, BC032138, BC020800, BC008848, BC001125,
Species
human
UniGene ID
Hs.434937

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.