human PPIB shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-219549
Availability:
4-5 weeks
Name:
AAV-h-PPIB-shRNA
This is an AAV expressing shRNA for silencing of Human PPIB.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PPIB
- Gene Name
- peptidylprolyl isomerase B
- Gene ID
- 5479
- Gene Synonyms
- CYP-S1; CYPB; HEL-S-39; OI9; SCYLP
- ORF Size
- 651 bp
- RefSeq#
- NM_000942
- Gene Description
- PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
- UniGene ID
- Hs.434937
- HGNC ID
- HGNC:9255
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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