human METTL1 Over-expression AAV

Name 
AAV-h-METTL1
Cat No 
AAV-215327
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human METTL1.

AAV-215327
AAV-h-METTL1

Ready-to-use AAV expressing Human METTL1 (methyltransferase like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C12orf1; D1075-like gene product; methyltransferase-like protein 1; TRM8; TRMT8; tRNA (guanine(46)-N(7))-methyltransferase; tRNA (guanine-N(7)-)-methyltransferase; tRNA-(guanine(46)-N(7))-methyltransferase; tRNA(m7G46)-methyltransferase; YDL201w
Description (eCommerce)
Methyltransferase like 1 (METTL1) Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Description (Vector)
METTL1 is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.
Gene ID
4234
Gene Name (eCommerce)
methyltransferase like 1
Gene Name (Vector)
methyltransferase like 1
Gene Symbol
METTL1
HGNC ID
HGNC:7030
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
831
ORF Size (bp)
831 bp
Protein Name (eCommerce)
tRNA (guanine-N(7)-)-methyltransferase
RefSeq ID
NM_005371
RefSeq Synonyms
NM_023033, NM_005371, BC000550,
Research Areas
Metabolism/Metabolic Process,Methyltransferase,RNA Binding,RNA Processing,tRNA Binding
Research Areas (Faceted)
metabolism,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Methyltransferase like 1 (METTL1) Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
UniGene ID
Hs.42957
UniProt ID (eCommerce)
Q9UBP6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.