human METTL1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human METTL1.
shAAV-215327
AAV-h-METTL1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human METTL1 (methyltransferase like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C12orf1; D1075-like gene product; methyltransferase-like protein 1; TRM8; TRMT8; tRNA (guanine(46)-N(7))-methyltransferase; tRNA (guanine-N(7)-)-methyltransferase; tRNA-(guanine(46)-N(7))-methyltransferase; tRNA(m7G46)-methyltransferase; YDL201w
Description (eCommerce)
Methyltransferase like 1 (METTL1) Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Description (Vector)
METTL1 is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.
Gene ID
4234
Gene Name (eCommerce)
methyltransferase like 1
Gene Name (Vector)
methyltransferase like 1
Gene Symbol
METTL1
HGNC ID
HGNC:7030
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
831
ORF Size (bp)
831 bp
Protein Name (eCommerce)
tRNA (guanine-N(7)-)-methyltransferase
RefSeq ID
NM_005371
RefSeq Synonyms
NM_023033, NM_005371, BC000550,
Research Areas
Metabolism/Metabolic Process,Methyltransferase,RNA Binding,RNA Processing,tRNA Binding
Research Areas (Faceted)
metabolism,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Methyltransferase like 1 (METTL1) Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
UniGene ID
Hs.42957
UniProt ID (eCommerce)
Q9UBP6
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.