human ME1 Over-expression AAV

Name 
AAV-h-ME1
Cat No 
AAV-215225
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ME1.

AAV-215225
AAV-h-ME1

Ready-to-use AAV expressing Human ME1 (malic enzyme 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HUMNDME; MES
Description (Vector)
ME1 encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
Gene ID
4199
Gene Name (Vector)
malic enzyme 1
Gene Symbol
ME1
HGNC ID
HGNC:6983
ORF Size (aa)
1719
ORF Size (bp)
1719 bp
RefSeq ID
NM_002395
RefSeq Synonyms
NM_002395, BC025246,
Species
human
UniGene ID
Hs.21160

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.