human ME1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ME1.
shAAV-215225
AAV-h-ME1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ME1 (malic enzyme 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HUMNDME; MES
Description (Vector)
ME1 encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
Gene ID
4199
Gene Name (Vector)
malic enzyme 1
Gene Symbol
ME1
HGNC ID
HGNC:6983
ORF Size (aa)
1719
ORF Size (bp)
1719 bp
RefSeq ID
NM_002395
RefSeq Synonyms
NM_002395, BC025246,
Species
human
UniGene ID
Hs.21160
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.