human MARCH5 Over-expression AAV

Name 
AAV-h-MARCH5
Cat No 
AAV-215021
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MARCH5.

AAV-215021
AAV-h-MARCH5

Ready-to-use AAV expressing Human MARCH5 (membrane associated ring-CH-type finger 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MARCH-V; MITOL; RNF153
Description (Vector)
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 (PubMed 16936636)).(supplied by OMIM, Mar 2008)
Gene ID
54708
Gene Name (Vector)
membrane associated ring-CH-type finger 5
Gene Symbol
5-Mar
HGNC ID
HGNC:26025
ORF Size (aa)
837
ORF Size (bp)
837 bp
RefSeq ID
NM_017824
RefSeq Synonyms
NM_017824, BC015480,
Species
human
UniGene ID
Hs.573490

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.