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mouse MARCH5 shRNA silencing AAV

Name 
AAV-m-MARCH5-shRNA
Cat No 
shAAV-264258
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse March5.

shAAV-264258
AAV-m-MARCH5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse March5 (membrane-associated ring finger (C3HC4) 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1810015H18Rik; 2310008I22Rik; 2700055A20Rik; 5730499H23Rik; E130202O05Rik; MARCH-V; Marchv; MITOL; Rnf153
Description (Vector)
Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1.
Gene ID
69104
Gene Name (Vector)
membrane-associated ring finger (C3HC4) 5
Gene Symbol
5-Mar
ORF Size (aa)
837
ORF Size (bp)
837 bp
RefSeq ID
NM_027314
RefSeq Synonyms
NM_027314, NM_001164337, NM_001164336, BC132457, BC132455, BC107215, BC064752,
Species
mouse
UniGene ID
Mm.175989

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.