human MAG Over-expression AAV

Name 
AAV-h-MAG
Cat No 
AAV-214799
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MAG.

AAV-214799
AAV-h-MAG

Ready-to-use AAV expressing Human MAG (myelin associated glycoprotein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GMA; S-MAG; SIGLEC-4A; SIGLEC4A; SPG75
Description (Vector)
MAG is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Gene ID
4099
Gene Name (Vector)
myelin associated glycoprotein
Gene Symbol
MAG
HGNC ID
HGNC:6783
ORF Size (aa)
1749
ORF Size (bp)
1749 bp
RefSeq ID
NM_002361
RefSeq Synonyms
NM_080600, NM_002361, NM_001199216, BC093045, BC053347,
Species
human
UniGene ID
Hs.643440

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.