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human MAG shRNA silencing AAV

Name 
AAV-h-MAG-shRNA
Cat No 
shAAV-214800
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAG.

shAAV-214800
AAV-h-MAG-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAG (myelin associated glycoprotein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GMA; S-MAG; SIGLEC-4A; SIGLEC4A; SPG75
Description (Vector)
MAG is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Gene ID
4099
Gene Name (Vector)
myelin associated glycoprotein
Gene Symbol
MAG
HGNC ID
HGNC:6783
ORF Size (aa)
1749
ORF Size (bp)
1749 bp
RefSeq ID
NM_002361
RefSeq Synonyms
NM_080600, NM_002361, NM_001199216, BC093045, BC053347,
Species
human
UniGene ID
Hs.643440

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.