human MAD1L1 Over-expression AAV

Name 
AAV-h-MAD1L1
Cat No 
AAV-214774
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MAD1L1.

AAV-214774
AAV-h-MAD1L1

Ready-to-use AAV expressing Human MAD1L1 (MAD1 mitotic arrest deficient like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hMAD1; HsMAD1; MAD1; MAD1 mitotic arrest deficient like 1; MAD1-like protein 1; mitotic arrest deficient 1-like protein 1; mitotic checkpoint MAD1 protein homolog; mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1, yeast, homolog-like 1; PIG9; tax-binding protein 181; TP53I9; tumor protein p53 inducible protein 9; TXBP181
Description (eCommerce)
MAD1 (Mitotic Arrest Deficiency 1) is a component of the mitotic spindle-assembly checkpoint that ensures that all chromosomes are aligned at the metaphase plate before the onset of anaphase. MAD1 functions as a homodimer that interacts with and regulates MAD2. MAD1 may play a role in tumor suppression.
Description (Vector)
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
Gene ID
8379
Gene Name (eCommerce)
mitotic arrest deficient 1 like 1
Gene Name (Vector)
MAD1 mitotic arrest deficient like 1
Gene Symbol
MAD1L1
HGNC ID
HGNC:6762
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2157
ORF Size (bp)
2157 bp
Protein Name (eCommerce)
Mitotic spindle assembly checkpoint protein MAD1
RefSeq ID
NM_003550
RefSeq Synonyms
NM_003550, NM_001304525, NM_001304524, NM_001304523, NM_001013837, NM_001013836, BC009964,
Research Areas
Cancer,Cell Cycle,Cell Division,Cytoskeleton,Host-Virus Interactions,Mitochondrion,Tumor Suppressors/Oncoproteins,Viral Carcinogenesis
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics,infectious_disease
Species
human
Target Sentence
MAD1 (Mitotic Arrest Deficiency 1) is a component of the mitotic spindle-assembly checkpoint that ensures that all chromosomes are aligned at the metaphase plate before the onset of anaphase. MAD1 functions as a homodimer that interacts with and regulates MAD2. MAD1 may play a role in tumor suppression.
UniGene ID
Hs.654838
UniProt ID (eCommerce)
Q9Y6D9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.