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mouse MAD1L1 shRNA silencing Adenovirus

Name 
Ad-m-MAD1L1-shRNA
Cat No 
shADV-264068
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Mad1l1.

shADV-264068
Ad-m-MAD1L1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mad1l1 (MAD1 mitotic arrest deficient 1-like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI173502; AW550425; Mad1
Description (Vector)
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.
Gene ID
17120
Gene Name (Vector)
MAD1 mitotic arrest deficient 1-like 1
Gene Symbol
Mad1l1
ORF Size (aa)
2154
ORF Size (bp)
2154 bp
RefSeq ID
NM_010752
RefSeq Synonyms
NM_010752, BC010702,
Species
mouse
UniGene ID
Mm.27250

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.