human LAIR1 Over-expression AAV

Name
AAV-h-LAIR1

Cat No
AAV-213639

Availability
4-5 weeks

This is an AAV expressing Human LAIR1.

AAV-213639

AAV-h-LAIR1

Ready-to-use AAV expressing Human LAIR1 (leukocyte associated immunoglobulin like receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD305; LAIR-1

Description (Vector)

LAIR1 is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.

Gene ID

3903

Gene Name (Vector)

leukocyte associated immunoglobulin like receptor 1

Gene Symbol

LAIR1

HGNC ID

HGNC:6477

ORF Size (aa)

864

ORF Size (bp)

864 bp

RefSeq ID

NM_002287

RefSeq Synonyms

NM_021706, NM_002287, NM_001289027, NM_001289026, NM_001289025, NM_001289023, BC027899,

Species

human

UniGene ID

Hs.572535

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.