human IPO4 Over-expression AAV

Name 
AAV-h-IPO4
Cat No 
AAV-212345
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IPO4.

AAV-212345
AAV-h-IPO4

Ready-to-use AAV expressing Human IPO4 (importin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Imp4; imp4b; importin-4; importin-4b; ran-binding protein 4; ranBP4
Description (eCommerce)
Importin 4 mediates the nuclear import of RPS3A. In vitro, it mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. Additionally, along with importin 7, importin 4 has been shown to be involved in nuclear import of HIF-1alpha [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q8TEX9].
Gene ID
79711
Gene Name (eCommerce)
importin 4
Gene Name (Vector)
importin 4
Gene Symbol
IPO4
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3246
ORF Size (bp)
3246 bp
Protein Name (eCommerce)
Importin-4
RefSeq ID
NM_024658
RefSeq Synonyms
NM_024658, BC136759, BC110804,
Research Areas
Immunology,Signal Transduction,Transport
Research Areas (Faceted)
signal_transduction,immunology,cell_biology
Species
human
Target Sentence
Importin 4 mediates the nuclear import of RPS3A. In vitro, it mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. Additionally, along with importin 7, importin 4 has been shown to be involved in nuclear import of HIF-1alpha [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q8TEX9].
UniGene ID
Hs.411865
UniProt ID (eCommerce)
Q8TEX9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.