human IL6 Over-expression AAV

Name
AAV-h-IL6

Cat No
AAV-212200

Availability
4-5 weeks

Categories
AAV, Over-Expression

This is an AAV expressing Human IL6.

AAV-212200

AAV-h-IL6

Ready-to-use AAV expressing Human IL6 (interleukin 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6

Description (Vector)

IL6 encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.

Gene ID

3569

Gene Name (Vector)

interleukin 6

Gene Symbol

IL6

HGNC ID

HGNC:6018

ORF Size (aa)

639

RefSeq ID

NM_000600

RefSeq Synonyms

NM_001318095, NM_000600, BC015511,

Species

human

UniGene ID

Hs.654458

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.