human HRH1 Over-expression AAV

Name
AAV-h-HRH1

Cat No
AAV-211523

Availability
4-5 weeks

This is an AAV expressing Human HRH1.

AAV-211523

AAV-h-HRH1

Ready-to-use AAV expressing Human HRH1 (histamine receptor H1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

H1-R; H1R; HH1R; hisH1

Description (Vector)

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene ID

3269

Gene Name (Vector)

histamine receptor H1

Gene Symbol

HRH1

HGNC ID

HGNC:5182

ORF Size (aa)

1464

ORF Size (bp)

1464 bp

RefSeq ID

NM_000861

RefSeq Synonyms

NM_001098213, NM_001098212, NM_001098211, NM_000861, BC060802,

Species

human

UniGene ID

Hs.1570

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.