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human HRH1 shRNA silencing AAV

Name 
AAV-h-HRH1-shRNA
Cat No 
shAAV-211523
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HRH1.

shAAV-211523
AAV-h-HRH1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HRH1 (histamine receptor H1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
H1-R; H1R; HH1R; hisH1
Description (Vector)
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
3269
Gene Name (Vector)
histamine receptor H1
Gene Symbol
HRH1
HGNC ID
HGNC:5182
ORF Size (aa)
1464
ORF Size (bp)
1464 bp
RefSeq ID
NM_000861
RefSeq Synonyms
NM_001098213, NM_001098212, NM_001098211, NM_000861, BC060802,
Species
human
UniGene ID
Hs.1570

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.