human HPS5 Over-expression AAV

Name 
AAV-h-HPS5
Cat No 
AAV-211505
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HPS5.

AAV-211505
AAV-h-HPS5

Ready-to-use AAV expressing Human HPS5 (HPS5, biogenesis of lysosomal organelles complex 2 subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AIBP63; BLOC2S2
Description (Vector)
HPS5 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.
Gene ID
11234
Gene Name (Vector)
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
Gene Symbol
HPS5
HGNC ID
HGNC:17022
ORF Size (aa)
3048
ORF Size (bp)
3048 bp
RefSeq ID
NM_007216
RefSeq Synonyms
NM_181508, NM_181507, NM_007216, BC033640,
Species
human
UniGene ID
Hs.437599

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.