human HPS5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HPS5.
shAAV-211505
AAV-h-HPS5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HPS5 (HPS5, biogenesis of lysosomal organelles complex 2 subunit 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AIBP63; BLOC2S2
Description (Vector)
HPS5 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.
Gene ID
11234
Gene Name (Vector)
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
Gene Symbol
HPS5
HGNC ID
HGNC:17022
ORF Size (aa)
3048
ORF Size (bp)
3048 bp
RefSeq ID
NM_007216
RefSeq Synonyms
NM_181508, NM_181507, NM_007216, BC033640,
Species
human
UniGene ID
Hs.437599
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.