human HOXD4 Over-expression AAV

Name 
AAV-h-HOXD4
Cat No 
AAV-211480
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HOXD4.

AAV-211480
AAV-h-HOXD4

Ready-to-use AAV expressing Human HOXD4 (homeobox D4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B
Description (Vector)
HOXD4 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. HOXD4 is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.
Gene ID
3233
Gene Name (Vector)
homeobox D4
Gene Symbol
HOXD4
HGNC ID
HGNC:5138
ORF Size (aa)
768
ORF Size (bp)
768 bp
RefSeq ID
NM_014621
RefSeq Synonyms
NM_014621, BC074797, BC016763,
Species
human
UniGene ID
Hs.591609

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.