human HMGCS1 Over-expression AAV

Name 
AAV-h-HMGCS1
Cat No 
AAV-211284
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HMGCS1.

AAV-211284
AAV-h-HMGCS1

Ready-to-use AAV expressing Human HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble); HMG-CoA synthase; HMGCS; hydroxymethylglutaryl-CoA synthase, cytoplasmic
Description (eCommerce)
HMGCS1 (Hydroxymethylglutaryl-CoA synthase) condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q01581].
Gene ID
3157
Gene Name (eCommerce)
3-hydroxy-3-methylglutaryl-CoA synthase 1
Gene Name (Vector)
3-hydroxy-3-methylglutaryl-CoA synthase 1
Gene Symbol
HMGCS1
HGNC ID
HGNC:5007
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1563
ORF Size (bp)
1563 bp
Protein Name (eCommerce)
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
RefSeq ID
NM_002130
RefSeq Synonyms
NM_002130, NM_001330663, NM_001324224, NM_001324223, NM_001324222, NM_001324220, NM_001324219, NM_001098272, BC083514,
Research Areas
Brain Development,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,Signal Transduction
Research Areas (Faceted)
cell_biology,developmental_biology,metabolism,neurobiology,signal_transduction
Species
human
Target Sentence
HMGCS1 (Hydroxymethylglutaryl-CoA synthase) condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q01581].
UniGene ID
Hs.397729
UniProt ID (eCommerce)
Q01581

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.