human HFE Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-210991
Availability:
3-5 weeks
Name:
AAV-h-HFE
This is an AAV expressing Human HFE.
Request a Quote
Please enter your email address and we'll be in touch with more information:
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HFE
- Gene Name
- hemochromatosis
- Gene ID
- 3077
- Gene Synonyms
- HFE1; HH; HLA-H; MVCD7; TFQTL2
- ORF Size
- 1047 bp
- RefSeq#
- BC117201
- Gene Description
- HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
- UniGene ID
- Hs.233325
- HGNC ID
- HGNC:4886
Related Products
Control Products
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
Privacy Policy