human HFE shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-210991
Availability:
3-5 weeks
Name:
Ad-h-HFE-shRNA
This is an Adenovirus expressing shRNA for silencing of Human HFE.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HFE
- Gene Name
- hemochromatosis
- Gene ID
- 3077
- Gene Synonyms
- HFE1; HH; HLA-H; MVCD7; TFQTL2
- ORF Size
- 1047 bp
- RefSeq#
- NM_000410
- Gene Description
- HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
- UniGene ID
- Hs.233325
- HGNC ID
- HGNC:4886
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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