human HELB Over-expression AAV

Name 
AAV-h-HELB
Cat No 
AAV-210934
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HELB.

AAV-210934
AAV-h-HELB

Ready-to-use AAV expressing Human HELB (DNA helicase B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DHB; DNA helicase B; hDHB; helicase (DNA) B
Description (eCommerce)
DNA Helicase B unwinds duplex DNA with 5'-3' polarity. It has single-strand DNA-dependent ATPase and DNA helicase activities. DNA helicase B prefers ATP and dATP as substrates. During S phase, it may facilitate cellular recovery from replication stress [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NG08].
Description (Vector)
HELB encodes a DNA-dependent ATPase which catalyzes the unwinding of DNA necessary for DNA replication, repair, recombination, and transcription. HELB is thought to function specifically during the S phase entry of the cell cycle.
Gene ID
92797
Gene Name (eCommerce)
DNA helicase B
Gene Name (Vector)
DNA helicase B
Gene Symbol
HELB
HGNC ID
HGNC:17196
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3261
ORF Size (bp)
3261 bp
Protein Name (eCommerce)
DNA helicase B
RefSeq ID
NM_033647
RefSeq Synonyms
NM_033647, BC157019, BC148592,
Research Areas
Helicase Activity
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
DNA Helicase B unwinds duplex DNA with 5'-3' polarity. It has single-strand DNA-dependent ATPase and DNA helicase activities. DNA helicase B prefers ATP and dATP as substrates. During S phase, it may facilitate cellular recovery from replication stress [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NG08].
UniGene ID
Hs.505941
UniProt ID (eCommerce)
Q8NG08

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.