human HELB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HELB.
shAAV-210934
AAV-h-HELB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HELB (DNA helicase B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DHB; DNA helicase B; hDHB; helicase (DNA) B
Description (eCommerce)
DNA Helicase B unwinds duplex DNA with 5'-3' polarity. It has single-strand DNA-dependent ATPase and DNA helicase activities. DNA helicase B prefers ATP and dATP as substrates. During S phase, it may facilitate cellular recovery from replication stress [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NG08].
Description (Vector)
HELB encodes a DNA-dependent ATPase which catalyzes the unwinding of DNA necessary for DNA replication, repair, recombination, and transcription. HELB is thought to function specifically during the S phase entry of the cell cycle.
Gene ID
92797
Gene Name (eCommerce)
DNA helicase B
Gene Name (Vector)
DNA helicase B
Gene Symbol
HELB
HGNC ID
HGNC:17196
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3261
ORF Size (bp)
3261 bp
Protein Name (eCommerce)
DNA helicase B
RefSeq ID
NM_033647
RefSeq Synonyms
NM_033647, BC157019, BC148592,
Research Areas
Helicase Activity
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
DNA Helicase B unwinds duplex DNA with 5'-3' polarity. It has single-strand DNA-dependent ATPase and DNA helicase activities. DNA helicase B prefers ATP and dATP as substrates. During S phase, it may facilitate cellular recovery from replication stress [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NG08].
UniGene ID
Hs.505941
UniProt ID (eCommerce)
Q8NG08
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.