human GSR Over-expression AAV
This is an AAV expressing Human GSR.
AAV-210590
AAV-h-GSR
Ready-to-use AAV expressing Human GSR (glutathione-disulfide reductase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HEL-75; HEL-S-122m
Description (Vector)
GSR encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Gene ID
2936
Gene Name (Vector)
glutathione-disulfide reductase
Gene Symbol
GSR
HGNC ID
HGNC:4623
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
RefSeq ID
NM_000637
RefSeq Synonyms
NM_001195104, NM_001195103, NM_001195102, NM_000637, BC069244,
Species
human
UniGene ID
Hs.271510
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.