human GSR shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-210590
Availability:
4-5 weeks
Name:
AAV-h-GSR-shRNA
This is an AAV expressing shRNA for silencing of Human GSR.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GSR
- Gene Name
- glutathione-disulfide reductase
- Gene ID
- 2936
- Gene Synonyms
- HEL-75; HEL-S-122m
- ORF Size
- 1569 bp
- RefSeq#
- NM_000637
- Gene Description
- GSR encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
- UniGene ID
- Hs.271510
- HGNC ID
- HGNC:4623
Related Products
Product | Cat No. |
---|---|
AAV-h-GSR | AAV-210590 |
AAV-m-GSR | AAV-260837 |
Ad-h-GSR | ADV-210590 |
Ad-m-GSR | ADV-260837 |
AAV-m-GSR-shRNA | shAAV-260837 |
Ad-h-GSR-shRNA | shADV-210590 |
Ad-m-GSR-shRNA | shADV-260837 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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