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mouse GUCA1A shRNA silencing AAV

Name 
AAV-m-GUCA1A-shRNA
Cat No 
shAAV-260925
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Guca1a.

shAAV-260925
AAV-m-GUCA1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Guca1a (guanylate cyclase activator 1a (retina)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GC-A; Gcap1; Guca1; mGCAP1
Description (Vector)
Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
Gene ID
14913
Gene Name (Vector)
guanylate cyclase activator 1a (retina)
Gene Symbol
Guca1a
ORF Size (aa)
609
RefSeq ID
NM_008189
RefSeq Synonyms
NM_008189, BC031810, BC026834,
Species
mouse
UniGene ID
Mm.16224

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.