human GRIN1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-210521
Availability:
3-5 weeks
Name:
AAV-h-GRIN1
This is an AAV expressing Human GRIN1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GRIN1
- Gene Name
- glutamate ionotropic receptor NMDA type subunit 1
- Gene ID
- 2902
- Gene Synonyms
- GluN1; MRD8; NMD-R1; NMDA1; NMDAR1; NR1
- ORF Size
- 2814 bp
- RefSeq#
- BC156097
- Gene Description
- GRIN1 is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
- UniGene ID
- Hs.558334
- HGNC ID
- HGNC:4584
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