human GABRA5 Over-expression AAV

Name 
AAV-h-GABRA5
Cat No 
AAV-209510
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GABRA5.

AAV-209510
AAV-h-GABRA5

Ready-to-use AAV expressing Human GABRA5 (gamma-aminobutyric acid type A receptor alpha5 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
Gene ID
2558
Gene Name (Vector)
gamma-aminobutyric acid type A receptor alpha5 subunit
Gene Symbol
GABRA5
HGNC ID
HGNC:4079
ORF Size (aa)
1389
ORF Size (bp)
1389 bp
RefSeq ID
NM_000810
RefSeq Synonyms
NM_001165037, NM_000810, BC113422, BC111979,
Species
human
UniGene ID
Hs.612087

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.