human GABRA5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GABRA5.
shAAV-209510
AAV-h-GABRA5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GABRA5 (gamma-aminobutyric acid type A receptor alpha5 subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
Gene ID
2558
Gene Name (Vector)
gamma-aminobutyric acid type A receptor alpha5 subunit
Gene Symbol
GABRA5
HGNC ID
HGNC:4079
ORF Size (aa)
1389
ORF Size (bp)
1389 bp
RefSeq ID
NM_000810
RefSeq Synonyms
NM_001165037, NM_000810, BC113422, BC111979,
Species
human
UniGene ID
Hs.612087
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.