human FLT1 Over-expression AAV

Name
AAV-h-FLT1

Cat No
AAV-209160

Availability
4-5 weeks

This is an AAV expressing Human FLT1.

AAV-209160

AAV-h-FLT1

Ready-to-use AAV expressing Human FLT1 (fms related tyrosine kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FLT; FLT-1; VEGFR-1; VEGFR1

Description (Vector)

FLT1 encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Gene ID

2321

Gene Name (Vector)

fms related tyrosine kinase 1

Gene Symbol

FLT1

HGNC ID

HGNC:3763

ORF Size (aa)

2064

ORF Size (bp)

2064 bp

RefSeq ID

NM_002019

RefSeq Synonyms

NM_002019, NM_001160031, NM_001160030, NM_001159920, BC039007,

Species

human

UniGene ID

Hs.654360

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.